Search results for "POLYMER HYBRID NANOPARTICLES"

showing 2 items of 2 documents

Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA

2020

Cells 9(9), 2034 (1-19) (2020). doi:10.3390/cells9092034

0301 basic medicine570small angle scatteringNanoparticlecationic lipid02 engineering and technologyengineering.materialTransfectionArticleCell LineFatty Acids Monounsaturated03 medical and health sciencesMiceBiopolymersddc:570AnimalsHumansRNA MessengerParticle Sizelcsh:QH301-705.5chemistry.chemical_classificationMice Inbred BALB Ccancer immunotherapySmall-angle X-ray scatteringHeparinOptical ImagingCationic polymerizationGeneral MedicinePolymerTransfection021001 nanoscience & nanotechnologyvaccinationSmall-angle neutron scatteringLipidslipid-polymer hybrid nanoparticlesQuaternary Ammonium Compounds030104 developmental biologychemistrylcsh:Biology (General)cationic polymerBiophysicsengineeringNanoparticlesRNAFemalePolymer blendBiopolymer0210 nano-technologyCovid-19
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Gated mesoporous silica nanoparticles for the controlled delivery of drugs in cancer cells

2015

In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective supports for the development of controlled-release nanodevices that are able to act as multifunctional delivery platforms for the encapsulation of therapeutic agents, enhancing their bioavailability and overcoming common issues such as poor water solubility and poor stability of some drugs. In particular, redox-responsive delivery systems have attracted the attention of scientists because of the intracellular reductive environment related to a high concentration of glutathione (GSH). In this context, we describe herein the development of a GSH-responsive delivery system based on poly(ethylene glycol)- (PEG-)…

INGENIERIA DE LA CONSTRUCCIONCell SurvivalIntracellular SpaceNanoparticleNanotechnologyAntineoplastic AgentsCONTROLLED-RELEASETRIGGERED RELEASEPolyethylene Glycolschemistry.chemical_compoundINORGANIC NANOPARTICLESQUIMICA ORGANICASYSTEMSPEG ratioQUIMICA ANALITICAElectrochemistrymedicinePOLYMER HYBRID NANOPARTICLESGLUTATHIONEBIOQUIMICA Y BIOLOGIA MOLECULARHumansGeneral Materials ScienceDoxorubicinSpectroscopyDrug CarriersENHANCED PERMEABILITYQUIMICA INORGANICASurfaces and InterfacesGlutathioneIN-VITROMesoporous silicaCondensed Matter PhysicsSilicon DioxideControlled releaseGUEST MOLECULESBioavailabilityDrug LiberationchemistryDoxorubicinDelayed-Action PreparationsDrug DesignNanoparticlesPhenazinesSUPPORTSEthylene glycolOxidation-ReductionPorositymedicine.drugHeLa Cells
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